The EU has warned COVID-19 vaccine producers they must deliver agreed supplies, amid fears reductions could seriously hamper its inoculation drive.
AstraZeneca and Pfizer-BioNTech have both said production problems mean they cannot supply the expected numbers.
The EU warned it could restrict exports of vaccines made in the bloc, with Germany's health minister demanding fair distribution.
The UK's vaccine minister warned of the dead end of vaccine nationalism.
AstraZeneca is mainly produced in the UK, while the UK's supplies of the Pfizer-BioNTech vaccine come from that company's Belgian plant.