The US is warning of an imminent attack in the Saudi city of Dhahran, a major centre for the oil industry.
Meanwhile, US President Donald Trump told Iran it is too late to talk, adding that their air defense, air force, navy, and leadership are gone.
Israel says it carried out new attacks on Iran's leadership compound on Tuesday, including the presidential office and in Tehran, infrastructure and sites used by the Iranian regime to produce weapons.
The Red Crescent says the number of people killed in Iran since US-Israeli attacks began on Saturday has reached 787.
Iran's Supreme Leader Ayatollah Ali Khamenei was among those killed.
The country has retaliated with a wave of attacks across the region.
On international markets, oil and gas prices are up, while share prices are down.
The UK government has announced its first charter flight to bring people back from the region; it will leave Oman in the coming days.
The UK is also sending a significant level of defensive capability to Cyprus, after attacks on a British base there, and is considering sending a warship.
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