Breezes Trelawny Resort and Spa is scheduled to close today ahead of a change in ownership.
Superclubs announced in March that the resort will be taken over by an overseas operator.
The positions of 200 workers will be made redundant.
Head of Superclubs, John Issa, said job opportunities may arise with the new operator.
Although not giving details, Mr. Issa explained that the sale was a welcomed option based on the plans the new operators have for the property, and the potential benefit for the area.